20 Million Canadians suffer from gut pain. Recently Health Canada has issued a Natural Health Product (NPN) license for C-Nag for managing the symptoms of Inflammatory Bowel Diseases including Crohn's, Celiac, Ulcerative Colitis and Rheumatoid Arthritis.
Recommended use or purpose:
Helps promote a healthy intestinal lining in people with symptoms associated with inflammatory bowel disease
Helps the body to metabolize fats and proteins
Helps in the development and maintenance of bones, cartilage, teeth and gums.
Helps in connective tissue formation
Helps in wound healing
An antioxidant for the maintenance of good health.
Adults: For healthy intestinal lining: take 6 capsules daily,in divided dose, or as directed by a health care practitioner.
All other claims: take 2 capsules daily in divided dose, or as directed by a health care practitioner.
"I have been taking C-NAG for my Crohn's disease about 6 weeks, I noticed a remarkable difference after only 1 week. I have not had any Crohns pain for more than 30 days. I have a slight bowel problem only if I over do it with my diet. I have a lot of confidence in C-NAG."*
Ruth, Kamloops, BC, Canada
"I am happy to say that after taking C-NAG, my Irritable Bowel Syndrome (IBS) had been helped and cleared up - I no longer have diarrhea."
"It is not often that I am moved to write glowing letters of praise.
Within six months of commencing 6 capsules of NAG daily, I decreased my intake of medication. When I became more pain free after five or six months and reduced my NAG intake to 4 capsules a day . . . ."
Cautions and warnings:
Consult a health care practitioner prior to use if you are pregnant or breastfeeding.
Do not use this product if you are allergic to shellfish.
If symptoms persist or worsen, consult a health care practitioner.
If seal around cap is broken or missing, do not use.
What are amino sugars?
Amino sugars are essential components of all body tissues, being integral parts of cell membranes and their surface structures, and of the interstitial tissue which holds cells together. About half of the interstitial tissue components are derived from amino sugars.
As the name implies, an amino sugar is made up of a sugar and an amino group. While most sugars come from dietary sources and are burned for energy, amino sugars are mainly formed within the body and used only in manufacturing tissue components.
Normal wear and tear during body functions means that tissues are constantly broken down and replaced or restructured, and amino sugars are thus continuously in demand. Any loss during such turnover will be made good by synthesis from glucose, since dietary supplies of amino sugars are usually low.
How is NAG produced?
Glucose first interacts with glutamine (an amino acid) to form glucosamine, with the help of a key enzyme (Glucosamine synthetase) which regulates the whole production line. An acetyl group is next added, and the product is N-acetyl-glucosamine (NAG).
Glucose heads a family of sugars with identical sets of atoms but slightly different shapes of the molecules. Other members in the group include galactose and mannose. Like NAG, these include the amino sugars N-acetyl-galactosamine and N-acetyl mannosamine. All are extensively involved in tissue building. NAG is the chief precursor of the whole family.
How does NAG serve the body?
Amino sugars variously combine with proteins, lipids (fats) or long chains of amino sugar units to form huge molecules (macromolecules) which become part of basic tissue components.
Glycoproteins are proteins with one or more short sugar chains which significantly modify the properties of these proteins. Such chains are attached onto newly formed proteins through amino sugar linkages. Some glycoproteins are important components of many enzymes and hormones; other remain on cell surfaces where their “antennae” of oligosaccharide (sugar) chains perform special functions, e.g., as blinding sites for circulating hormones and for recognition between cells (the grouping of different cells to form a tissue depends on proper recognition of one cell surface by another).
The sugar chains may also determine the antigenic property of the glycoprotein so that the immune system can identify the body’s own cells from foreign ones. Mucus is a special glycoprotein with a high sugar content which accounts for its very viscous nature.
C-NAG® can be used alone or in addition to other immunoregulatory drugs to increase efficacy and decrease dosage and toxicity.
C-NAG® may provide the first therapeutic approach that directly targets an underlying disease causal mechanism, human clinical trials are warranted.
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